C15 - Clearance Identification

The Benchmark C15 Clearance Identification is based on the dynamics of renal clearance. The benchmark puts emphasis on identification of a compartmental model for the clearance using real-word measurement protocols, and on statistical model parameter analysis based on artificial protocols.

This benchmark allows to study different identification approaches for a linear dynamic system, e.g. use of sensitivity functions or use of analytical solutions, and to handle artificial data protocols for extended experiments – a useful basis for teaching of both topics, independent on the physiological background.

Modellers and simulationists are invited to prepare, to realise, and to submit a

  • C15 Benchmark Solution with concise description of model implementation and modified identification tasks (two pages SNE), or a
  • C15 Benchmark Report with additional model identification variants considering linear structures (four to six pages SNE).